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Absence of mutation in the putative tumor-suppressor gene KLF6 in colorectal cancers

✍ Scribed by Lièvre, Astrid; Landi, Bruno; Côté, Jean-François; Veyrie, Nicolas; Zucman-Rossi, Jessica; Berger, Anne; Laurent-Puig, Pierre

Book ID
110069909
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
147 KB
Volume
24
Category
Article
ISSN
0950-9232

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Loss of heterozygosity (LOH) on chromosome 10 is the most common genetic changes in glioblastomas of World Health Organization (WHO) Grade IV. [1][2][3][4][5][6][7] In most cases, the allelic losses involve loci along the entire chromosome, a finding in line with monosomy 10. LOH on chromosome 10 ma