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Klotho Acts as a Tumor Suppressor in Cancers

✍ Scribed by Biao Xie, Jinhui Chen, Bin Liu, Junkun Zhan


Book ID
120957607
Publisher
Springer Netherlands
Year
2013
Tongue
English
Weight
264 KB
Volume
19
Category
Article
ISSN
1219-4956

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## Abstract The specific deletion of __Rb__ gene in epidermis leads to altered proliferation and differentiation, but not to the development of spontaneous tumors. Our previous data have demonstrated the existence of a functional compensation of __Rb__ loss by __Rbl1__ (p107) in as the phenotypic d