MKK4 acts as a potential tumor suppressor in ovarian cancer
✍ Scribed by Shamima Yeasmin; Kentaro Nakayama; Mohammed Tanjimur Rahman; Munmun Rahman; Masako Ishikawa; Atsuko Katagiri; Kouji Iida; Naomi Nakayama; Kohji Miyazaki
- Book ID
- 107693927
- Publisher
- S. Karger AG
- Year
- 2011
- Tongue
- English
- Weight
- 514 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1010-4283
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The specific deletion of __Rb__ gene in epidermis leads to altered proliferation and differentiation, but not to the development of spontaneous tumors. Our previous data have demonstrated the existence of a functional compensation of __Rb__ loss by __Rbl1__ (p107) in as the phenotypic d
## Abstract In the current study, we investigated the mechanism relating downregulation of mitogen‐activated protein kinase kinase 4 (MKK4) expression to development of ovarian cancer. Over‐expression of the MKK4 gene in TOV‐21 G cells, a line with homozygous deletion of MKK4, resulted in morpholog