Kirsten ras mutations in patients with colorectal cancer: the ‘RASCAL II’ study
✍ Scribed by Andreyev, H J N; Norman, A R; Cunningham, D; Oates, J; Dix, B R; Iacopetta, B J; Young, J; Walsh, T; Ward, R; Hawkins, N; Beranek, M; Jandik, P; Benamouzig, R; Jullian, E; Laurent-Puig, P; Olschwang, S; Muller, O; Hoffmann, I; Rabes, H M; Zietz, C; Troungos, C; Valavanis, C; Yuen, S T; Ho, J W C; Croke, C T; O’Donoghue, D P; Giaretti, W; Rapallo, A; Russo, A; Bazan, V; Tanaka, M; Omura, K; Azuma, T; Ohkusa, T; Fujimori, T; Ono, Y; Pauly, M; Faber, C; Glaesener, R; Goeij, A F P M de; Arends, J W; Andersen, S N; Lövig, T; Breivik, J; Gaudernack, G; Clausen, O P F; Angelis, P De; Meling, G I; Rognum, T O; Smith, R; Goh, H-S; Font, A; Rosell, R; Sun, X F; Zhang, H; Benhattar, J; Losi, L; Lee, J Q; Wang, S T; Clarke, P A; Bell, S; Quirke, P; Bubb, V J; Piris, J; Cruickshank, N R; Morton, D; Fox, J C; Al-Mulla, F; Lees, N; Hall, C N; Snary, D; Wilkinson, K; Dillon, D; Costa, J; Pricolo, V E; Finkelstein, S D; Thebo, J S; Senagore, A J; Halter, S A; Wadler, S; Malik, S; Krtolica, K; Urosevic, N
- Book ID
- 119981119
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 50 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0007-0920
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Mutant-enriched PCR was applied to the detection of mutations at codons I 2 and I 3 of K-ras genes in the stools of patients with colorectal cancer. Mutations were analyzed in stool samples obtained prior to surgery. Resected tumor specimens were screened for K-ras mutations by PCR-mediated RFLP ana