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Kinetics of competitive inhibition of salicylic acid conjugation with glycine in man

โœ Scribed by Gerhard Levy; Lewis P. Amsel

Book ID
115769286
Publisher
Elsevier Science
Year
1966
Tongue
English
Weight
285 KB
Volume
15
Category
Article
ISSN
0006-2952

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๐Ÿ“œ SIMILAR VOLUMES

Drug biotransformation interactions in m
Drug biotransformation interactions in man II: A pharmacokinetic study of the simultaneous conjugation of Benzoic and Salicylic Acids with Glycine
โœ Lewis P. Amsel; Gerhard Levy ๐Ÿ“‚ Article ๐Ÿ“… 1969 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 587 KB

The major route of biotransformation of benzoic acid and salicylic acid in man is conjugation with glycine, resulting in the formation of hippuric acid and salicyluric acid, respectively. Both processes are capacity-limited in the usual dose range and approach a maximum rate following administration