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Inter-individual differences in the glycine conjugation of salicylic acid [proceedings]

โœ Scribed by J Caldwell; J O'Gorman; RL Smith

Book ID
117942328
Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
144 KB
Volume
9
Category
Article
ISSN
0306-5251

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๐Ÿ“œ SIMILAR VOLUMES

Drug biotransformation interactions in m
Drug biotransformation interactions in man II: A pharmacokinetic study of the simultaneous conjugation of Benzoic and Salicylic Acids with Glycine
โœ Lewis P. Amsel; Gerhard Levy ๐Ÿ“‚ Article ๐Ÿ“… 1969 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 587 KB

The major route of biotransformation of benzoic acid and salicylic acid in man is conjugation with glycine, resulting in the formation of hippuric acid and salicyluric acid, respectively. Both processes are capacity-limited in the usual dose range and approach a maximum rate following administration