Kinetics and mechanism of the N7-hydroxyalkylation of guanosine
β Scribed by Robert Roe Jr.; J. S. Paul; P. O'B. Montgomery
- Book ID
- 112123045
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1973
- Tongue
- English
- Weight
- 412 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0022-152X
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π SIMILAR VOLUMES
## Abstract The kinetics of the reaction between __N__β(2βhydroxyalkyl) hydroparabanates (HAHP) and __N,N__β²βbis(2βhydroxyalkyl) parabanates (HAP) with ethylene and propylene oxides were studied. The addition of oxiranes to imide function of HAHP led to the formation of HAP. Further reaction of HAP
Rate constants for the reaction of oxiranes with bis/2-hydroxyalkyl/disulfides, bis/2-hydroxyalkyllsulfides, and 1,6-hexanediol in the presence of N,N-dimethylcyclohexylamine were studied at the temperature range of 50-90Β°C. A mechanism of these reactions has been proposed and its kinetic equation h