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Kinetics and mechanism of acyl transfer by penicillin acylases

✍ Scribed by J. Konecny; M. Sieber; A. Schneider

Book ID
104641746
Publisher
Springer Netherlands
Year
1981
Tongue
English
Weight
291 KB
Volume
3
Category
Article
ISSN
0141-5492

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Kinetics and mechanism of acyl transfer
Kinetics and mechanism of acyl transfer by penicillin acylases
✍ Jan Konecny; AndrΓ© Schneider; Meinrad Sieber πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 English βš– 721 KB

## Abstract The hypothesis that at least some penicillin acylases react via an acyl–enzyme intermediate was tested by kinetic investigations involving the methyl ester of cyanoacetic acid as the acyl donor, deacetyl‐7‐aminocephalosporanic acid as the acyl receptor, and penicillin acylase (E.C.3.5.1