Lipase B from Candida antarctica (CAL-B) catalyses the highly enantioselective (E > 200) transesterification of some 1-biaryl-2-yl-, -3-yl-, and -4-ylethanols and -propan-1-ols, as well as 1-(o-, m-, and p-pyridylphenyl)ethanols, 6, with vinyl acetate, Kazlauskas rule being obeyed in all cases. meta
Kinetic resolution of trans-2-(1-pyrazolyl)cyclohexan-1-ol catalyzed by lipase B from Candida antarctica
✍ Scribed by M. Barz; E. Herdtweck; W.R. Thiel
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 299 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0957-4166
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Kinetic resolution of a series of racemic trans-cycloalkane-1,2-diol monoacetates rac-2a-d was performed by enantiomerically selective transesterification with vinyl acetate catalysed by commercial and our own-prepared fungal lipases to yield diacetates (R,R)-3a-d and monoacetates (S,S)-2a-d in high
Enantiomerically pure (R)-l-phenylethylamine and ethyl rac-2methyloctanoate in the presence of lipase from Candidada antarctica (Novozym 435) reacted to give (R)-2-methyloctanoic (R)-l-phenylethylamide as the predominant diastereomer of 30 -40% de at = 100% conversion. Ethyl rac-2-methyldecanoate an