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Kinetic resolution of acyclic 1,2-diols using a sequential lipase-catalyzed transesterification in organic solvents

✍ Scribed by Theil, Fritz; Weidner, Judith; Ballschuh, Sibylle; Kunath, Annamarie; Schick, Hans


Book ID
118745117
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
751 KB
Volume
59
Category
Article
ISSN
0022-3263

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Lipase-catalysed kinetic resolution of p
✍ Karin Lemke; Fritz Theil; Annamarie Kunath; Hans Schick πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 183 KB

The enantiomer selectivity of the kinetic resolution of phenylethan-l,2-diol [(RS)-I] by sequential acetylation with vinyl acetate in the presence of lipase from Pseudomonas cepacia (Amano PS) was investigated for dependence on the solvent. Optimal conditions for the resolution of (RS)-I are present