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Lipase-catalysed kinetic resolution of phenylethan-1,2-diol by sequential transesterification — the influence of the solvent

✍ Scribed by Karin Lemke; Fritz Theil; Annamarie Kunath; Hans Schick

Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 183 KB
Volume: 7
Category: Article
ISSN: 0957-4166
DOI: 10.1016/0957-4166(96)00094-8

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✦ Synopsis

The enantiomer selectivity of the kinetic resolution of phenylethan-l,2-diol [(RS)-I] by sequential acetylation with vinyl acetate in the presence of lipase from Pseudomonas cepacia (Amano PS) was investigated for dependence on the solvent. Optimal conditions for the resolution of (RS)-I are presented.

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