The enantiomer selectivity of the kinetic resolution of phenylethan-l,2-diol [(RS)-I] by sequential acetylation with vinyl acetate in the presence of lipase from Pseudomonas cepacia (Amano PS) was investigated for dependence on the solvent. Optimal conditions for the resolution of (RS)-I are present
β¦ LIBER β¦
The resolution of racemic 1,2-diols by the esterase catalysed hydrolysis of the corresponding cyclic carbonate
β Scribed by Patrick Barton; Michael I Page
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- French
- Weight
- 164 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0040-4020
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β¦ Synopsis
Racemic 1-phenyl-1,2-ethane dial can be resolved by the pig liver esterase catalysed hydrolysis of the corresponding cyclic carbonate to give the (R) and (S) 1-phenyl-1,2-ethane diol with an ee of 97 and 78% respectively.
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