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The resolution of racemic 1,2-diols by the esterase catalysed hydrolysis of the corresponding cyclic carbonate

✍ Scribed by Patrick Barton; Michael I Page


Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
164 KB
Volume
48
Category
Article
ISSN
0040-4020

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✦ Synopsis


Racemic 1-phenyl-1,2-ethane dial can be resolved by the pig liver esterase catalysed hydrolysis of the corresponding cyclic carbonate to give the (R) and (S) 1-phenyl-1,2-ethane diol with an ee of 97 and 78% respectively.


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