Lipase-catalyzed kinetic resolution of 3-hydroxy esters in organic solvents and supercritical carbon dioxide
✍ Scribed by A. Capewell; V. Wendel; U. Bornscheuer; H.H. Meyer; T. Scheper
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 733 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0141-0229
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📜 SIMILAR VOLUMES
## Abstract The first straightforward lipase‐catalyzed enantioselective access to enantiomerically enriched tiaprofenic acid as a versatile method in chiral separation of racemates is demonstrated. The latter was directly monitored by enantioselective HPLC using a 3,5‐dimethylphenylcarbamate deriva
## Abstract By enzyme‐catalyzed intramolecular transesterification methyl (±)‐(3__R__\*,5__S__\*,6__E__)‐3,5‐dihydroxy‐7‐phenyl‐6‐heptenoate (__rac__‐4) can be enantioselectively converted into the δ‐lactone 5. An enantiomeric excess of 80% was obtained by Pancreatin in diethyl ether at ambient tem