Kinetic Assay for High-Throughput Screening of In Vitro Transthyretin Amyloid Fibrillogenesis Inhibitors
✍ Scribed by Dolado, Ignacio; Nieto, Joan; Saraiva, Maria João M.; Arsequell, Gemma; Valencia, Gregori; Planas, Antoni
- Book ID
- 126393897
- Publisher
- American Chemical Society
- Year
- 2005
- Tongue
- English
- Weight
- 143 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1520-4766
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## Abstract Amyloid β peptide (Aβ) fibril formation is widely believed to be the causative event of Alzheimer’s disease pathogenesis. Therapeutic approaches are therefore in development that target various sites in the production and aggregation of Aβ. Herein we present a high‐throughput screening