Killing of non-Hodgkin lymphoma cells by autologous CD19 engineered T cells
β Scribed by Eleanor J. Cheadle; David E. Gilham; Fiona C. Thistlethwaite; John A. Radford; Robert E. Hawkins
- Book ID
- 108673144
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 323 KB
- Volume
- 129
- Category
- Article
- ISSN
- 0007-1048
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This article describes the study of the functional relationship between auto-tumor-reactive CD4 + T cell clones (TCC) and autologous malignant B cells. Four auto-tumor-reactive CD4 + TCC were derived from tumor-infiltrating T lymphocytes (TIL-T) from a freshly isolated human follicular lymphoma by t
group (those with complete remission CR or partial remission PR) and a significant positive correlation was found in the nonresponders group (those with stable disease [SD] or progressive Disease [PD]) (P < 0.001). Correlation of CD38 with the initial response was significant (P = 0.034) when using