In line with our ancestors: Oct-4 and th
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Maurizio Pesce; Michael K. Gross; Hans R. SchΓΆler
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Article
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1998
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John Wiley and Sons
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English
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The transcription factor Oct-4 is expressed specifically in the totipotent germline cycle of mice. Cells that lose Oct-4 differentiate along different paths to form embryonic and extraembryonic somatic tissue. Oct-4 may maintain the potency of stem and germline cells by preventing all other differen