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JAK2-V617F mutation analysis of granulocytes and platelets from patients with chronic myeloproliferative disorders: advantage of studying platelets

โœ Scribed by Kohtaro Toyama; Masamitsu Karasawa; Arito Yamane; Hiroyuki Irisawa; Akihiko Yokohama; Takayuki Saitoh; Hiroshi Handa; Takafumi Matsushima; Morio Sawamura; Shuichi Miyawaki; Hirokazu Murakami; Yoshihisa Nojima; Norifumi Tsukamoto


Book ID
108675378
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
549 KB
Volume
139
Category
Article
ISSN
0007-1048

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Correlations of JAK2โ€“V617F mutation with
โœ Matthaios Speletas; Eirini Katodritou; Chrisoula Daiou; Eudokia Mandala; Emmanou ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 212 KB

Recently, the acquired mutation JAK2-V617F has been described in the majority of patients with myeloproliferative disorders (MPDs). In this study we evaluated its clinical and laboratory correlates in 166 patients with MPDs. The mutation was detected by allele-specific PCR in 119 patients: 81.4% (35