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Incidence and significance of theJAK2V617F mutation in patients with chronic myeloproliferative disorders

โœ Scribed by S. E. Langabeer; F. Ni Ainle; E. Conneally; M. Lawler


Book ID
107525940
Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
166 KB
Volume
176
Category
Article
ISSN
1863-4362

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Correlations of JAK2โ€“V617F mutation with
โœ Matthaios Speletas; Eirini Katodritou; Chrisoula Daiou; Eudokia Mandala; Emmanou ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 212 KB

Recently, the acquired mutation JAK2-V617F has been described in the majority of patients with myeloproliferative disorders (MPDs). In this study we evaluated its clinical and laboratory correlates in 166 patients with MPDs. The mutation was detected by allele-specific PCR in 119 patients: 81.4% (35