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Jab1 is overexpressed in human breast cancer and is a downstream target for HER-2/neu

✍ Scribed by Hsu, Ming-Chuan; Chai, Chee-Yin; Hou, Ming-Feng; Chang, Hui-Chiu; Chen, Wan-Tzu; Hung, Wen-Chun

Book ID
109887639
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
380 KB
Volume
21
Category
Article
ISSN
0893-3952

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## Abstract ## BACKGROUND The overexpression of HER‐2/__neu__ is found in 20–30% of patients with breast carcinoma and is an adverse prognostic factor. HER‐2 overexpression also has been reported in up to 60% of patients with hormone‐refractory prostate carcinoma (HRPC) and was correlated with sho