Resistance to tamoxifen-induced apoptosi
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Yih-Lin Chung; Meei-Ling Sheu; Shun-Chun Yang; Chi-Hung Lin; Sang-Hue Yen
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Article
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2001
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John Wiley and Sons
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French
โ 498 KB
## Abstract Overexpression of Her2/neu is implicated in the development of resistance to the antiestrogen tamoxifen (TAM) that exerts its inhibitory effect through interaction with estrogen receptor (ER). Whereas Her2/neu and ER are believed to be important cell survival/death factors in human brea