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Association between HER-2/neu and the progesterone receptor in oestrogen-dependent breast cancer is age-related

โœ Scribed by Huei-Jean Huang; Patrick Neven; Maria Drijkoningen; Robert Paridaens; Hans Wildiers; Erik Van Limbergen; Patrick Berteloot; Frederic Amant; Marie Rose Christiaens; Ignace Vergote


Publisher
Springer US
Year
2005
Tongue
English
Weight
202 KB
Volume
91
Category
Article
ISSN
0167-6806

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## Abstract Overexpression of Her2/neu is implicated in the development of resistance to the antiestrogen tamoxifen (TAM) that exerts its inhibitory effect through interaction with estrogen receptor (ER). Whereas Her2/neu and ER are believed to be important cell survival/death factors in human brea