✦ LIBER ✦

The Wnt antagonist DICKKOPF-1 gene is a downstream target of β-catenin/TCF and is downregulated in human colon cancer

✍ Scribed by González-Sancho, José Manuel; Aguilera, Oscar; García, José Miguel; Pendás-Franco, Natalia; Peña, Cristina; Cal, Santiago; de Herreros, Antonio García; Bonilla, Félix; Muñoz, Alberto

Book ID: 110069365
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 176 KB
Volume: 24
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1208303

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

DICKKOPF-4 is induced by TCF/β-catenin a

DICKKOPF-4 is induced by TCF/β-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1α,25-dihydroxyvitamin D3

✍ Pendás-Franco, N; García, J M; Peña, C; Valle, N; Pálmer, H G; Heinäniemi, M; Ca 📂 Article 📅 2008 🏛 Nature Publishing Group 🌐 English ⚖ 524 KB

HDPR1, a novel inhibitor of the WNT/β-ca

HDPR1, a novel inhibitor of the WNT/β-catenin signaling, is frequently downregulated in hepatocellular carcinoma: involvement of methylation-mediated gene silencing

✍ Yau, Tai-On; Chan, Chung-Yiu; Chan, Kok-Lung; Lee, Man-Fong; Wong, Chun-Ming; Fa 📂 Article 📅 2004 🏛 Nature Publishing Group 🌐 English ⚖ 305 KB

Promoter methylation of the Wnt/β-cateni

Promoter methylation of the Wnt/β-catenin signaling antagonist Dkk-3 is associated with poor survival in gastric cancer

✍ Jun Yu; Qian Tao; Yuen Y. Cheng; Kwan Y. Lee; Simon S. M. Ng; Kin F. Cheung; Lin 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 352 KB 👁 1 views

## Abstract ## BACKGROUND: Abnormal activation of the Wnt/β‐catenin signaling pathway is common and critical in the pathogenesis of digestive cancers. In this study, the authors investigated the promoter methylation of the dickkopf homolog 3 gene __Dkk‐3__ in these cancers and its prognostic signi

KAI1/CD82 is a novel target of estrogen

KAI1/CD82 is a novel target of estrogen receptor-mediated gene repression and downregulated in primary human breast cancer

✍ Matthias Christgen; Henriette Bruchhardt; Matthias Ballmaier; Till Krech; Floria 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 749 KB

## Abstract The cell‐surface glycoprotein KAI1 suppresses tumor growth and metastasis in various animal models. Downregulation of KAI1 has been implicated in the progression of cancer. However, the mechanisms of KAI1 inactivation are poorly understood. This is the first study that investigates expr

KAI1/CD82 is a novel target of estrogen

KAI1/CD82 is a novel target of estrogen receptor-mediated gene repression and downregulated in primary human breast cancer (Int J Cancer 123: 2239–2246, 2008)

✍ Joseph Geradts 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 43 KB 👁 1 views

With interest I read the article by Christgen et al. that was recently published under the Fast Track heading in the International Journal of Cancer. 1 The major reported findings, nicely summarized in the article's title, are that (a) KAI1/CD82 is downregulated in 77% of human breast carcinomas and