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Isolation of monosialylated oligosaccharides from human milk and structural analysis of three new compounds

✍ Scribed by Gunnar Grönberg; Peter Lipniunas; Torgny Lundgren; Karin Erlansson; Frank Lindh; Bo Nilsson


Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
927 KB
Volume
191
Category
Article
ISSN
0008-6215

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✦ Synopsis


The monosialyated oligosaccharide fraction from combined samples of human milk was fractionated by gel filtration, ion-exchange chromatography, and h.p.l.c. with triethylamine as an ion-pairing reagent. Among the twelve oligosaccharides isolated, three were new compounds for which the following structures were established on the basis of chemical analyses, f.a.b.-m.s., and n.m.r. spectroscopy.


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