Isolation, identification and synthesis of an endogenous arachidonic amide that inhibits calcium channel antagonist 1,4-dihydropyridine binding
β Scribed by Johnson, D.E.; Heald, S.L.; Dally, R.D.; Janis, R.A.
- Book ID
- 123172775
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 941 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0952-3278
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## Abstract Nifedipine analogs I, II and III with the 2__H__β1βbenzopyranβ2βone (coumarin) fluorophore linked at the 2, 2 and 6 and 4 positions of the dihydropyridine ring were synthesized by the modified Hantzch condensation procedures. Attempts to synthesize dihydropyridine with the fluorophore a
Synthesis and Binding Properties of 2H-1-Benzopyran-2-one Fluorophore-Linked Calcium Channel Antagonist Nifedipine (1,4-Dihydropyridine) Analogues. -Nifedipine analogues (VII), (VIII), and (XI) with a coumarin fluorophore linked at the 2-, 2,6-, and 4-position of the dihydropyridine ring, resp., are