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Isolation, genetics and survival characteristics of thermo-sensitive mutants of yeast

✍ Scribed by Evans, W. E. ;Parry, James M.


Publisher
Springer
Year
1974
Tongue
English
Weight
542 KB
Volume
134
Category
Article
ISSN
0026-8925

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Isolation of the yeast phosphoglyceromut
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The PGM1 gene (also called GPM; Fraenkel 1982) coding for phosphoglyceromutase was isolated by functional complementation. When present on a multicopy vector and introduced into yeast cells it led to an about eightfold increase in specific enzymatic activity. This apparent overproduction was confirm