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Isolation of yeast mutants sensitive to the bifunctional alkylating agent nitrogen mustard

โœ Scribed by Ruhland, Axel ;Haase, Eckard ;Siede, Wolfram ;Brendel, Martin


Publisher
Springer
Year
1981
Tongue
English
Weight
674 KB
Volume
181
Category
Article
ISSN
0026-8925

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Isolation and characterization of yeast
โœ Wolfram Siede; Martin Brendel ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 479 KB

Selection of mutants of Saccharomyces cerevisiae sensitive to the DNA cross-linking agent nitrogen mustard (HN2) at two temperatures (23 ยฐC and 36 ยฐC) yielded two isolates with thermoconditionally enhanced (ts) sensitivity to the mutagen. Both were due to single recessive nuclear genes. Mutant allel