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Isolation and sequence of theGCR3 homologue fromCandida albicans by complementation of Δgcr3 strain ofSaccharomyces cerevisiae

✍ Scribed by Uemura, Hiroshi; Nakamoto, Keiko; Sugioka, Shigemi; Tadenuma, Maki

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
247 KB
Volume
15
Category
Article
ISSN
0749-503X

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✦ Synopsis

To study the function of GCR3, a gene involved in the expression of glycolytic genes in Saccharomyces cerevisiae, a Candida albicans gene which complements the growth defect of the gcr3 mutant was isolated. Transformants of this gene also recovered the glycolytic enzyme activities. Its DNA sequencing predicted an 886 amino acid protein with 30•4% identity to the Gcr3p of S. cerevisiae. Its DDBJ/EMBL/GenBank Accession Number is AB015281.

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