## Abstract Huntington's disease (HD) is a progressive, autosomal dominant neurodegenerative disease caused by an abnormally expanded CAG repeat in the HD gene. Ubiquitylated aggregates containing mutant huntingtin protein in neurons are hallmarks of HD. Misfolded mutant huntingtin monomers, oligom
✦ LIBER ✦
Is the ubiquitin-proteasome system impaired in Huntington’s disease?
✍ Scribed by Z. Ortega; M. Díaz-Hernández; J. J. Lucas
- Book ID
- 105758669
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 418 KB
- Volume
- 64
- Category
- Article
- ISSN
- 1420-682X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Ubiquitin-proteasome system alterations
✍
Jesse M. Hunter; Mathieu Lesort; Gail V.W. Johnson
📂
Article
📅
2007
🏛
John Wiley and Sons
🌐
English
⚖ 505 KB
Global changes to the ubiquitin system i
✍
Bennett, Eric J.; Shaler, Thomas A.; Woodman, Ben; Ryu, Kwon-Yul; Zaitseva, Tati
📂
Article
📅
2007
🏛
Nature Publishing Group
🌐
English
⚖ 453 KB
“Theory of mind” is impaired in Huntingt
✍
Martin Brüne; Karina Blank; Henning Witthaus; Carsten Saft
📂
Article
📅
2011
🏛
John Wiley and Sons
🌐
English
⚖ 118 KB
👁 1 views
## Abstract ## Background: Huntington's disease (HD) is an autosomal dominant degenerative brain disorder that is characterized by motor, cognitive, and affective symptoms. There is, to some, degree, phenomenological overlap with schizophrenia. Schizophrenia patients are frequently impaired in “th
OPINION: Failure of the ubiquitin–
✍
McNaught, Kevin St P.; Olanow, C. Warren; Halliwell, Barry; Isacson, Ole; Jenner
📂
Article
📅
2001
🏛
Nature Publishing Group
🌐
English
⚖ 254 KB
Seek and destroy: The ubiquitin-proteaso
✍
Jessica E. Rodríoguez; Jonathan C. Schisler; Cam Patterson; Monte S. Willis
📂
Article
📅
2009
🏛
Springer
🌐
English
⚖ 424 KB
The ubiquitin proteasome system in neuro
✍
Norman L. Lehman
📂
Article
📅
2009
🏛
Springer-Verlag
🌐
English
⚖ 581 KB