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Irreversible and Reversible Deactivation of Bilirubin Oxidase by Urate

✍ Scribed by Hyosul Shin; Chan Kang; Adam Heller


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
99 KB
Volume
19
Category
Article
ISSN
1040-0397

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Urate oxidase from Candida utilis, an enzyme containing an essential thiol, was examined for its sensitivity to lactoperoxidase, an oxidant present in breast milk. Upon exposure to a system composed of lactoperoxidase, hydrogen peroxide and bromide at moderately alkaline pH, the urate oxidase exhibi