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Irradiation inhibits the regeneration of aneurogenic limbs

✍ Scribed by Wallace, H. ;Maden, M.

Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
526 KB
Volume
195
Category
Article
ISSN
0022-104X

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✦ Synopsis

Abstract

The developing arms of axolotl larvae from the 2‐digit stage onward and the aneurogenic arms of surgically denervated larvae maintained in parabiosis are able to regenerate after amputation. Such regeneration is uniformly inhibited by local irradiation of the arm, whether innervated or not. This demonstration refutes a recent hypothesis that X‐rays interfere with a special activity of nerves required for regeneration, and supports the earlier concept that X‐rays act directly on those cells which must proliferate to form the regenerated tissues.

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