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Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial

✍ Scribed by JY Douillard; D Cunningham; AD Roth; M Navarro; RD James; P Karasek; P Jandik; T Iveson; J Carmichael; M Alakl; G Gruia; L Awad; P Rougier

Book ID
117275314
Publisher
The Lancet
Year
2000
Tongue
English
Weight
106 KB
Volume
355
Category
Article
ISSN
0140-6736

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Randomised trial of irinotecan plus supp
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Background In phase II studies, irinotecan is active in metastatic colorectal cancer, but the overall benefit has not been assessed in a randomised clinical trial. Methods Patients with proven metastatic colorectal cancer, which had progressed within 6 months of treatment with fluorouracil, were ra

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