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Cost-effectiveness analysis of irinotecan plus fluorouracil/folinic acid compared with fluorouracil/folinic acid alone as first-line treatment for advanced colorectal cancer

✍ Scribed by Warren Mark Hart; Carlos Rubio-Terrés; Linda Pronk; Svetlana Kobina; Eduardo Díaz Rubio


Book ID
110646319
Publisher
Springer Milan
Year
2003
Tongue
Spanish
Weight
188 KB
Volume
5
Category
Article
ISSN
1699-048X

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Background. Metastatic colorectal cancer is generally incurable. The most active regimen available, 5-fluorouracil(5-FU) and folinic acid (Leucovorin), produces response rates of approximately 25% to 30%. Methyl-lomustine is a nitrosourea with modest activity against colorectal cancer. A randomized