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Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer

✍ Scribed by David Cunningham; Seppo Pyrhönen; Roger D James; Cornelis JA Punt; Tamas F Hickish; Reino Heikkila; Tom B Johannesen; Hans Starkhammar; Clare A Topham; Lucile Awad; Christian Jacques; Patrice Herait


Book ID
117311216
Publisher
The Lancet
Year
1998
Tongue
English
Weight
169 KB
Volume
352
Category
Article
ISSN
0140-6736

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Randomised trial of irinotecan plus supp
✍ David Cunningham; Seppo Pyrhönen; Roger D James; Cornelis JA Punt; Tamas F Hicki 📂 Article 📅 1998 🏛 The Lancet 🌐 English ⚖ 169 KB

Background In phase II studies, irinotecan is active in metastatic colorectal cancer, but the overall benefit has not been assessed in a randomised clinical trial. Methods Patients with proven metastatic colorectal cancer, which had progressed within 6 months of treatment with fluorouracil, were ra