Randomised trial of irinotecan plus supp
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David Cunningham; Seppo Pyrhönen; Roger D James; Cornelis JA Punt; Tamas F Hicki
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Article
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1998
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The Lancet
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English
⚖ 169 KB
Background In phase II studies, irinotecan is active in metastatic colorectal cancer, but the overall benefit has not been assessed in a randomised clinical trial. Methods Patients with proven metastatic colorectal cancer, which had progressed within 6 months of treatment with fluorouracil, were ra