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Involvement of Urokinase-Type Plasminogen Activator System in Cancer: An Overview

✍ Scribed by Mekkawy, Ahmed H.; Pourgholami, Mohammad H.; Morris, David L.

Book ID
121785175
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
465 KB
Volume
34
Category
Article
ISSN
0198-6325

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The urokinase-type plasminogen activator (u-PA) system consists of the serine proteinases plasmin and u-PA; the serpin inhibitors a 2 -anti-plasmin, PAI-1 and PAI-2; and the u-PA receptor (u-PAR). Two lines of evidence have strongly suggested an important and apparently causal role for the u-PA syst