𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Involvement of the Ink4 proteins p16 and p15 in T-lymphocyte senescence

✍ Scribed by Erickson, Sven; Sangfelt, Olle; Heyman, Mats; Castro, Juan; Einhorn, Stefan; Grandér, Dan


Book ID
110061453
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
365 KB
Volume
17
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Alterations of p16INK4A and p15INK4B gen
✍ Young Y. Lee; Shin H. Kang; Jin Y. Seo; Chul W. Jung; Kuhn U. Lee; Kuk J. Choe; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 199 KB 👁 1 views

## Background: It has been suggested that cyclin-dependent kinase inhibitors (cdkis), including p16 and p15, are tumor suppressor genes. alterations of cdkis have been found in most types of cancer. however, little is known about the status of p16 and p15 genes, including methylation of the promote

Expression of p16INK4A variants in senes
✍ Wineeta K.C. Weebadda; Tonya J. Jackson; Athena W. Lin 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 305 KB

## Abstract Upregulation of the p16 tumor suppressor is a hallmark of senescence in human fibroblasts. In this study, we investigated potential protein modification of p16 in senescent human fibroblasts using 2D SDS–PAGE analysis. Three distinct p16 variants with isoelectric points of 5.2, 5.4, and