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Involvement of p-15INK4b and p-16INK4a Gene Expression in Saikosaponin a and TPA-Induced Growth Inhibition of HepG2 Cells

✍ Scribed by Wen-Sheng Wu; Hsue-Yin Hsu

Book ID
115588215
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
148 KB
Volume
285
Category
Article
ISSN
0006-291X

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## Background: It has been suggested that cyclin-dependent kinase inhibitors (cdkis), including p16 and p15, are tumor suppressor genes. alterations of cdkis have been found in most types of cancer. however, little is known about the status of p16 and p15 genes, including methylation of the promote