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Involvement of mitochondrial- and Fas-mediated dual mechanism in CoCl2-induced apoptosis of rat PC12 cells

✍ Scribed by Ji-Yeon Jung; Won-Jae Kim

Book ID
116766971
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
340 KB
Volume
371
Category
Article
ISSN
0304-3940

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## Abstract It is widely known that death receptor Fas‐dependent apoptotic signals are associated with development of prostate cancer, but the key pathways involved in sensitivity to the apoptosis remain unclear. Here we investigated the molecular mechanism by which 2‐methoxyestradiol (2‐ME) effect