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Lead-induced apoptosis in PC 12 cells: Involvement of p53, Bcl-2 family and caspase-3

✍ Scribed by Jin Xu; Lin-Dan Ji; Li-Hong Xu

Book ID
119378701
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
310 KB
Volume
166
Category
Article
ISSN
0378-4274

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## Abstract Our previous study showed that cobalt chloride (CoCl~2~) could induce PC12 cell apoptosis and that the CoCl~2~‐treated PC12 cells may serve as a simple in vitro model for the study of the mechanism of hypoxia‐linked neuronal disorders. The aim of this study is to elucidate the mechanism