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Involvement of K+ channels in the relaxant effect of vasoactive intestinal peptide and atrial natriuretic peptide in isolated guinea-pig trachea

✍ Scribed by Steffen Thirstrup; Jens Erik Nielsen-Kudsk; Søren Mellemkjær

Book ID
117098997
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
115 KB
Volume
319
Category
Article
ISSN
0014-2999

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Effect of atrial natriuretic peptide and
Effect of atrial natriuretic peptide and on atriopeptins on the human isolated bronchus. Comparison with the reactivity of the guinea-pig isolated trachea
✍ M-L. Candenas; E. Naline; L. Puybasset; P. Devillier; C. Advenier 📂 Article 📅 1991 🏛 Elsevier 🌐 English ⚖ 521 KB

ANF, ANF7-28 and atriopeptins (AP1, AP2 and AP3) (10(-11) to 3 x 10(-7) M) induce a relaxant response on the guinea-pig isolated trachea, which is partially potentiated by the enkephalinase inhibitor thiorphan 10(-5) M but is unmodified by epithelium removal. Conversely, these drugs were found to be