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Involvement of cyclic GMP in the fusion of chick embryonic myoblasts in culture

✍ Scribed by Suk Woo Choi; Mi Yeong Baek; Man-Sik Kang

Book ID: 115892733
Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 545 KB
Volume: 199
Category: Article
ISSN: 0014-4827
DOI: 10.1016/0014-4827(92)90470-s

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## Abstract Theophylline, a cyclic nucleotide phosphodiesterase inhibitor, increases the rate of tyrosine aminotransferase (TAT) degradation in rat hepatoma tissue culture (HTC) cells. Theophylline (0.1–10 mM) causes a two‐ to five‐fold increase in intracellular cAMP concentration but a 30–60% decr