Investigations on the toxicological profile of functionalized fifth-generation poly(propylene imine) dendrimer
β Scribed by Hrushikesh B. Agashe; Tathagata Dutta; Minakshi Garg; N. K. Jain
- Book ID
- 111770470
- Publisher
- Pharmaceutical Press
- Year
- 2006
- Tongue
- English
- Weight
- 264 KB
- Volume
- 58
- Category
- Article
- ISSN
- 2042-7158
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Dendrimers are well-defined highly branched macromolecules that emanate from a central core and are synthesized through a stepwise, repetitive reaction sequence. In this study, different generations of a poly(propylene imine) dendrimer have been functionalized with second-order non-linear optical ch
The use of preformed poly(propylene imine) dendrimers surface concentration variations on the dendrimer properties. After modification of the dendrimers with these saccharide [DAB(Pa) x ] with reactive primary amine end groups proved to be very useful for the construction of saccharide surface-unit
A molecular dynamics study of poly(propylene imine)-based dendrimers, with end groups modified with tBoc-protected l-phenylalanyl amino acids, has been performed. Five generations of the dendrimer with 4, 8, 16, 32 and 64 amino acids were considered. The shape of the dendrimer was found to be genera