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Investigation of the Role of Lipoxygenase in Bioactivation of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Human Lung

✍ Scribed by Bedard, Leanne L.; Smith, Graeme B. J.; Reid, Ken R.; Petsikas, Dimitri; Massey, Thomas E.

Book ID
121357524
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
71 KB
Volume
15
Category
Article
ISSN
0893-228X

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## Abstract Urinary metabolites of the tobacco‐specific nitrosamine 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK), 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol (NNAL) and its glucuronides, termed total NNAL, have recently been shown to be good predictors of lung cancer risk, years before di