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Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human placental microsomes

✍ Scribed by Néstor R. Collazo; Lester G. Sultatos

Book ID
115784446
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
875 KB
Volume
50
Category
Article
ISSN
0006-2952

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Genetic variability in the metabolism of
Genetic variability in the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL)
✍ Monica Ter-Minassian; Kofi Asomaning; Yang Zhao; Feng Chen; Li Su; Steven G. Car 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 354 KB

## Abstract Urinary metabolites of the tobacco‐specific nitrosamine 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK), 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol (NNAL) and its glucuronides, termed total NNAL, have recently been shown to be good predictors of lung cancer risk, years before di