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4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism-related enzymes gene polymorphisms, NNK metabolites levels and urothelial carcinoma

✍ Scribed by Chung, Chi-Jung; Pu, Yeong-Shiau; Shiue, Horng-Sheng; Lee, Hui-Ling; Lin, Pinpin; Yang, Hsiu-Yuan; Su, Chien-Tien; Hsueh, Yu-Mei


Book ID
119381911
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
259 KB
Volume
216
Category
Article
ISSN
0378-4274

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## Abstract Urinary metabolites of the tobacco‐specific nitrosamine 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK), 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol (NNAL) and its glucuronides, termed total NNAL, have recently been shown to be good predictors of lung cancer risk, years before di