Inversion recovery TrueFISP: Quantification of T1, T2, and spin density

✍ Scribed by Peter Schmitt; Mark A. Griswold; Peter M. Jakob; Markus Kotas; Vikas Gulani; Michael Flentje; Axel Haase

• Book ID: 102953726
• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 557 KB
• Volume: 51
• Category: Article
• ISSN: 0740-3194
• DOI: 10.1002/mrm.20058

✦ Synopsis

Abstract

A novel procedure is proposed to extract T~1~, T~2~, and relative spin density from the signal time course sampled with a series of TrueFISP images after spin inversion. Generally, the recovery of the magnetization during continuous TrueFISP imaging can be described in good approximation by a three parameter monoexponential function S(t) = S~stst~(1‐INV exp(‐t/T). This apparent relaxation time T ≤ T~1~ depends on the flip angle as well as on both T~1~ and T~2~. Here, it is shown that the ratio T~1~/T~2~ can be directly extracted from the inversion factor INV, which describes the relation of the signal value extrapolated to t = 0 and the steady‐state signal. Analytical expressions are given for the derivation of T~1~, T~2~, and relative spin density directly from the fit parameters. Phantom results show excellent agreement with single point reference measurements. In human volunteers T~1~, T~2~, and spin density maps in agreement with literature values were obtained. Magn Reson Med 51:661–667, 2004. © 2004 Wiley‐Liss, Inc.