## Abstract A novel procedure is proposed to extract __T__~1~, __T__~2~, and relative spin density from the signal time course sampled with a series of TrueFISP images after spin inversion. Generally, the recovery of the magnetization during continuous TrueFISP imaging can be described in good appr
T1 quantification with inversion recovery TrueFISP
✍ Scribed by Klaus Scheffler; Jürgen Hennig
- Book ID
- 102529155
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 208 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0740-3194
- DOI
- 10.1002/mrm.1097
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✦ Synopsis
Abstract
A snapshot FLASH sequence can be used to acquire the time course of longitudinal magnetization during its recovery after a single inversion pulse. However, excitation pulses disturb the exponential recovery of longitudinal magnetization and may produce systematic errors in T~1~ estimations. In this context the possibility of using the TrueFISP sequence to detect the recovery of longitudinal magnetization for quantitative T~1~ measurements was examined. Experiments were performed on different Gd‐doped water phantoms and on humans. T~1~ values derived from inversion recovery TrueFISP were in excellent agreement with the single‐point method even for flip angles up to 50°. In terms of T~1~ accuracy and SNR, the proposed method seems to be superior to the conventional inversion recovery snapshot FLASH technique. Magn Reson Med 45:720–723, 2001. © 2001 Wiley‐Liss, Inc.
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