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Novel method for rapid, simultaneous T1, T*2, and proton density quantification

✍ Scribed by J.B.M. Warntjes; O. Dahlqvist; P. Lundberg

Book ID
102532853
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
440 KB
Volume
57
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

An imaging method called “quantification of relaxation times and proton density by twin‐echo saturation‐recovery turbo‐field echo” (QRAPTEST) is presented as a means of quickly determining the longitudinal T~1~ and transverse T relaxation time and proton density (PD) within a single sequence. The method also includes an estimation of the B~1~ field inhomogeneity. High‐resolution images covering large volumes can be achieved within clinically acceptable times of 5–10 min. The range of accuracy for determining T~1~, T, and PD values is flexible and can be optimized relative to any anticipated values. We validated the experimental results against existing methods, and provide a clinical example in which quantification of the whole brain using 1.5 mm^3^ voxels was achieved in less than 8 min. Magn Reson Med 57:528–537, 2007. © 2007 Wiley‐Liss, Inc.

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