Intrinsically Disordered Protein Analysis: Volume 1, Methods and Experimental Tools

✍ Scribed by Peter Tsvetkov, Yosef Shaul (auth.), Vladimir N. Uversky, A. Keith Dunker (eds.)

• Publisher: Humana Press
• Year: 2012
• Tongue: English
• Leaves: 511
• Series: Methods in Molecular Biology 895
• Edition: 1
• Category: Library

✦ Synopsis

Over the past decade, there has been an explosive development of research of intrinsically disordered proteins (IDPs), which are also known as unfolded proteins. Structural biologists now recognize that the functional diversity provided by disordered regions complements the functional repertoire of ordered protein regions.In Intrinsically Disordered Protein Analysis :Methods and Experimental Tools, expert researchers explorethe high abundance of IDPs in various organisms, their unique structural features, numerous functions, and crucial associations with different diseases. Volume 1 includes sections on assessing IDPs in the living cell,NMR based techniques, vibrational spectroscopy, and other spectroscopic techniques. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.

Thorough and intuitive,Intrinsically Disordered Protein Analysis: Methods and Experimental Tools helps scientists further their investigations of these fascinating and dynamic molecules.

✦ Table of Contents

Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Front Matter....Pages 3-18
Front Matter....Pages 19-31
Front Matter....Pages 33-41
Back Matter....Pages 43-54
....Pages 55-66

✦ Subjects

Protein Science; Protein Structure