Intrinsic viscosity of poly(α-L-glutamic acid) in N-methylacetamide
✍ Scribed by Daniel K. Schiffer; Alfred Holtzer
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1974
- Tongue
- English
- Weight
- 247 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0006-3525
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✦ Synopsis
It is well known that poly(a-cglutamic acid) (PLGA) undergoes a helix to randomcoil transition in aqueous media when the macromolecule is charged by titration with base. This behavior is clearly revealed by studies of optical properties [i.e., ultraviolet absorption and optical rotatory dispersion (ORD) or circular dichroism (CD)] and of
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## Abstract Interaction of poly‐α,L‐glutamic acid (PGLA) with acridine orange (AO) was studied with circular dichroism and absorption spectra measurements. The following results were observed: (1) the addition of a comparable amount of AO with the glutamyl residue to the PLGA solution at pH of 4.5
## Abstract A polarimetric electric‐field‐jump relaxation apparatus is described and used to determine the relaxation spectrum for the helix–coil transition of poly(α,L‐glutamic acid) in water at 24°C. A maximum relaxation time of 1.7 μc occurs at the transition midpoint (pH = 5.9) yielding a rate
The optical rotatory dispersion in the range 630-340 mp has been measured for aqueous solutions of the tetramethylammonium salt of a-poly-L-glutamic acid to compare the effects produced by added tetramethylammonium chloride and magnesium chloride at equivalent ionic strengths. The addition of magnes