An 11-year-old boy with a life-long history of atopic-like dermatitis and recurrent staphylococcal abscesses was found to have defective neutrophil chemotaxis, impaired-T-lymphocyte functions, hyperimmunoglobulinemia E, and delayed neutrophil bactericidal power. This latter defect has never been fou
Intrinsic neutrophil defects in a child with impaired neutrophil chemotaxis and immunodeficiency
β Scribed by Dr. Hironori Morosawa; Munehiro Yamazaki; Kenichi Sugita; Hiroharu Saitoh; Atsushi Komiyama; Taro Akabane
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 588 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0361-8609
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A new defect of chemotaxis and random motility of polymorphonuclear leukocytes is described in a patient with severe recurrent bacterial infections since early childhood. This defect seems to be intrinsic to the cells. The patient's plasma did not contain an inhibitor of chemotaxis. Addition of plas
We have recently described a chemotactic defect in severely afflicted Gaucher disease patients. Two of the patients were treated with low-dose intravenous enzyme replacement (Ceredase). Marked improvement in their hematological status, organomegaly, and growth was observed. In addition, their chemot