✦ LIBER ✦

Correction of neutrophil chemotaxis defect in patients with gaucher disease by low-dose enzyme replacement therapy

✍ Scribed by Dr. A. Zimran; A. Abrahamov; M. Aker; Y. Matzner

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 192 KB
Volume: 43
Category: Article
ISSN: 0361-8609
DOI: 10.1002/ajh.2830430118

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✦ Synopsis

We have recently described a chemotactic defect in severely afflicted Gaucher disease patients. Two of the patients were treated with low-dose intravenous enzyme replacement (Ceredase). Marked improvement in their hematological status, organomegaly, and growth was observed. In addition, their chemotactic defect and their tendency towards infections were corrected within 1 year of treatment.

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